Spis publikacji od utworzenia Zakładu Fizykochemicznej Analizy Leku

2026

• P. J. Bernard, A. Więckowska, S. Grosjean, J. Godyń,Godyń, K. Sałat, J. Detka, N. Palacz, W. Tyrybon, J. J. Jończyk, N. Szałaj, P. Zaręba, H. Ne Martin, M. Maj, K. Jozwiak, J. Marco-Contelles, L. Ismaili, “First Sustainable One-Pot Tandem Hantzsch Multicomponent Reaction/Click Reaction Approach for Novel Multitarget-Directed Ligands in Alzheimer’s Disease” ACS Chem. Neurosci. 2026, 17, 422.
• D. Rysanek, Z. Chrienova, D. Stary, M. Bajda, J. Novak, P. Vasicova, J. Kroupova, R. Andrys, A. Skarka, E. Rousarova, J. Capek, T. Rousar, Z. Milovanovic, J. Grujic-Milanovic, V. Jacevic, J. N. Kolla, M. Popr, D. Maurencova, P. Oleksak, L. Fresser, K. Kuca, Z. Hodny, E. Nepovimova, “In silico screening, synthesis, and biological evaluation of pyrazolopyrimidine-derived mTOR inhibitors for anticancer and senomorphic effects” Cancer Cell Int. 2026
• D. Stary, A. El-Kasaby, D. Boytsov, P. Zaręba, J. Godyń, M. Maszczyk, Z. Rzepka, D. Wrześniok, C. Sotriffer, W. Sandtner, M. Freissmuth, M. Bajda, “Structure-Based Search for Novel Creatine Transporter Inhibitors” ACS Med. Chem. Lett. 2026, 17, 1355–1363.
• T. Gidaga, J. Kukułowicz, M. Ogos, M. Bajda, “Molecular modeling of the orphan SLC6A16 transporter revealed an unusual composition of the substrate transport pathway” Phys. Biol. 2026, 23
• M. Toledano-Pinedo, A. Porro-Pérez, L. Schäker-Hübner, D. Diez-Iriepa, I. Iriepa, A. Siwek, M. Wolak, G. Satała, A. J. Bojarski, A. Doroz-Płonka, J. Handzlik, J. Godyń, P. Dallemagne, C. Rochais, A. Davis, M. Since, B. Pérez, A. Bellver-Sanchis, A. Irisarri, M. Pallàs, C. Solana-Manrique, F. López-Muñoz, L. Ismaili, C. Griñán-Ferré, N. Paricio, F. K Hansen, A. Więckowska, J. Marco-Contelles, “Polyfunctionalized N-Arylsulfonyl Indoles: Identification of (E)- N-Hydroxy-3-{3-[(5-(3-(piperidin-1-yl)propoxy]-1 H-indol-1-yl)sulfonyl]phenyl}acrylamide (MTP150) for the Epigenetic-Based Therapy of Parkinson’s Disease” Int. J. Mol. Sci. 2026, 27
• R. Juza, A. Wieckowska, I. Vojtechova, K. Kuca, O. Soukup, J. Korabecny, T. Petrasek, “The role of 5-HT3 receptors in schizophrenia and associated depressive and addictive comorbidities” Prog. Neuropsychopharmacol. Biol. Psychiatry 2026, 146
• P. J. Bernard, A. Więckowska, S. Grosjean, J. Godyń,Godyń, K. Sałat, J. Detka, N. Palacz, W. Tyrybon, J. J. Jończyk, N. Szałaj, P. Zaręba, H. Ne Martin, M. Maj, K. Jozwiak, J. Marco-Contelles, L. Ismaili, “First Sustainable One-Pot Tandem Hantzsch Multicomponent Reaction/Click Reaction Approach for Novel Multitarget-Directed Ligands in Alzheimer’s Disease” ACS Chem. Neurosci. 2026, 17, 422

 2025

• J. Godyń, J. Jończyk, A. Więckowska, M. Bajda, “Integrative Profiling for BBB Permeability Using Capillary Electrochromatography, Experimental Physicochemical Parameters, and Ensemble Machine Learning” Int. J. Mol. Sci. 2025, 27
• K. Mizgalska, U. Al.-Aani, Y. Aljaidah, D. Panek, A. Chaari, M. Bajda, “Inhibition of Human Amylin Aggregation: In Silico and In Vitro Studies” ACS Omega 2025, 10, 52269–52288.
• D. Stary, M. Bajda, “Unveiling the Structure of PROT and ATB0,+: Unique Members of the Glycine Transporter Subfamily” Molecules 2025, 30
• M. Li, J. Gao, Y. Xie, Z. Zhu, L. Huang, Y. Lai, M. Yar, M. Bajda, M. Li, H. Yu, F. Wang, Z. Xu, “Molecular Rotor-Based NIR-II TICTgens for Mitochondria-Targeted Pyroptosis Induction and Multi-Model Monitoring of Cancer Immunotherapy” Angew. Chem. Int. Ed Engl. 2025, 64
• P. J. Bernard, A. Więckowska, S. Grosjean, J. Godyń,Godyń, K. Sałat, J. Detka, N. Palacz, W. Tyrybon, J. J. Jończyk, N. Szałaj, P. Zaręba, H. Ne Martin, M. Maj, K. Jozwiak, J. Marco-Contelles, L. Ismaili, “First Sustainable One-Pot Tandem Hantzsch Multicomponent Reaction/Click Reaction Approach for Novel Multitarget-Directed Ligands in Alzheimer’s Disease” ACS Chem. Neurosci. 2026, 17, 422
• J. Sniecikowska, M. Gluch-Lutwin, A. Bucki, B. Gryzlo, K. Wieckowski, J. Godyn, A. Wieckowska, A. Siwek, M. Jastrzebska-Wiesek, A. Partyka, A. Cios, A. Wesolowska, A. Newman-Tancredi, M. Kolaczkowski, “Discovery of NLX-266, an Orally Available and Metabolically Stable ERK1/2-Biased 5-HT1AR Agonist with Superior Antidepressant and Antiparkinsonian Activity” J. Med. Chem. 2025, 68, 9706–9722
• D. Kułaga, A. K. Drabczyk, P. Zaręba, J. Jaśkowska, G. Satała, P. Zaręba, A. Więckowska, M. de Candia, R. Purgatorio, A. Boguszewska-Czubara, S. Sudoł-Tałaj, G. Latacz, D. Plażuk, “Discovery of new dual butyrylcholinesterase (BuChE) inhibitors and 5-HT7 receptor antagonists as compounds used to treat Alzheimer’s disease symptoms” Biomedicine and Pharmacotherapy 2025, 186
• J. Godyń, J. Jończyk, A. Więckowska, M. Bajda, “Integrative Profiling for BBB Permeability Using Capillary Electrochromatography, Experimental Physicochemical Parameters, and Ensemble Machine Learning” Int. J. Mol. Sci. 2025, 27
• Ó. M. Bautista-Aguilera, A. Manik, D. Diez-Iriepa, N. Szałaj, P. Zaręba, A. Więckowska, P. Żmudzki, E. Honkisz-Orzechowska, D. Knez, S. Gobec, K. Sałat, B. Martínez-Alonso, V. Guarnizo-Herrero, G. T. Durán, C. Torrado-Salmerón, A. Bellver-Sanchis, I. Nsiona-Defise, M. Ribalta-Vilella, M. Pallàs, F. López-Muñoz, C. Griñán-Ferré, J. Marco-Contelles, I. Iriepa, “N-Methyl-N-((1-methyl-5-(3-(piperidin-1-yl)propoxy)-1H-benzo[d]imidazol-2-yl)methyl)prop-2-yn-1-amine (MBA-159), a new multitarget small molecule for the therapy of Alzheimer’s disease” Biomedicine and Pharmacotherapy 2025, 192
• J. Kukułowicz, A. Siwek, M. Wolak, A. Bröer, A. Yadav, S. Bröer, M. Bajda, “Insight into the Structure of the Neutral Amino Acid Transporter B0AT2 Enabled the Discovery of Tiagabine as an Inhibitor” ACS Chem. Neurosci. 2025, 16, 262–274.
• D. Panek, A. Pasieka, J. Jończyk, M. Gawlińska, P. Zaręba, A. Siwek, M. Wolak, B. Mordyl, M. Głuch-Lutwin, G. Latacz, X. Brazzolotto, F. Chantegreil, F. Nachon, J. Zdarova Karasova, J. Pejchal, M. Mzik, V. Sestak, L. Prchal, J. Odvarkova, O. Soukup, J. Korabecny, A. Sorf, M. Hamsikova, L. Zemanova, L. Muckova, N. Vánova, P. Dryja, K. Sałat, G. Höfner, K. Wanner, A. Więckowska, B. Malawska, “Multifunctional, Fluorene-Based Modulator of Cholinergic and GABAergic Neurotransmission as a Novel Drug Candidate for Palliative Treatment of Alzheimer’s Disease” Angew. Chem. Int. Ed Engl. 2025, 64

2024

• D. Stary, M. Bajda, “Structural Studies of the Taurine Transporter: A Potential Biological Target from the GABA Transporter Subfamily in Cancer Therapy” Int. J. Mol. Sci. 2024, 25, DOI 10.3390/IJMS25137339.
• J. Jończyk, K. Przybylska, M. Staszewski, J. Godyń, T. Werner, M. Stefaniak-Napieralska, H. Stark, K. Walczyński, M. Bajda, “Virtual Screening Approaches to Identify Promising Multitarget-Directed Ligands for the Treatment of Autism Spectrum Disorder” Molecules 2024, 29, DOI 10.3390/MOLECULES29225271.
• J. Kukułowicz, M. Bajda, “In silico structural studies on the vesicular neutral amino acid transporter NTT4 (SLC6A17)” Comput. Struct. Biotechnol. J. 2024, 23, 3342–3347.
• K. Łątka, S. Kickinger, Z. Rzepka, P. Zaręba, G. Latacz, A. Siwek, M. Wolak, D. Stary, M. Marcinkowska, P. Wellendorph, D. Wrześniok, M. Bajda, “Rational Search for Betaine/GABA Transporter 1 Inhibitors─ In Vitro Evaluation of Selected Hit Compound” ACS Chem. Neurosci. 2024, 15, 4046–4054.
• A. Bröer, Z. Hu, J. Kukułowicz, A. Yadav, T. Zhang, L. Dai, M. Bajda, R. Yan, S. Bröer, “Cryo-EM structure of ACE2-SIT1 in complex with tiagabine” Journal of Biological Chemistry 2024, 300, DOI 10.1016/j.jbc.2024.107687.
• M. Ogos, D. Stary, M. Bajda, “Recent Advances in the Search for Effective Anti-Alzheimer’s Drugs” Int. J. Mol. Sci. 2024, 26, DOI 10.3390/IJMS26010157.
• I. Góral, T. Wichur, E. Sługocka, J. Godyń, N. Szałaj, P. Zaręba, M. Głuch-Lutwin, B. Mordyl, D. Panek, A. Więckowska, “Connecting GSK-3β Inhibitory Activity with IKK-β or ROCK-1 Inhibition to Target Tau Aggregation and Neuroinflammation in Alzheimer’s Disease-Discovery, In Vitro and In Cellulo Activity of Thiazole-Based Inhibitors” Molecules 2024, 29, DOI 10.3390/MOLECULES29112616.
• M. Toledano-Pinedo, A. Porro-Pérez, L. Schäker-Hübner, F. Romero, M. Dong, A. Samadi, P. Almendros, I. Iriepa, Ò. M. Bautista-Aguilera, M. M. Rodríguez-Fernández, C. Solana-Manrique, I. Sanchis, A. Mora-Morell, A. C. Rodrìguez, A. M. Sànchez-Pérez, D. Knez, S. Gobec, A. Bellver-Sanchis, B. Pérez, A. V. Dobrydnev, A. Artetxe-Zurutuza, A. Matheu, A. Siwek, M. Wolak, G. Satała, A. J. Bojarski, A. Doroz-Płonka, J. Handzlik, J. Godyń, A. Więckowska, N. Paricio, C. Griñán-Ferré, F. K. Hansen, J. Marco-Contelles, “Contilisant+Tubastatin A Hybrids: Polyfunctionalized Indole Derivatives as New HDAC Inhibitor-Based Multitarget Small Molecules with In Vitro and In Vivo Activity in Neurodegenerative Diseases” J. Med. Chem. 2024, 67, 16533–16555.
• R. Malek, K. Sałat, P. Totoson, T. Karcz, B. Refouvelet, A. Skrzypczak-Wiercioch, M. Maj, A. Simakov, H. Martin, A. Siwek, N. Szałaj, J. Godyń, D. Panek, A. Więckowska, K. Jozwiak, C. Demougeot, K. Kieć-Kononowicz, F. Chabchoub, I. Iriepa, J. Marco-Contelles, L. Ismaili, “Discovery of New Highly Potent Histamine H3 Receptor Antagonists, Calcium Channel Blockers, and Acetylcholinesterase Inhibitors” ACS Chem. Neurosci. 2024, 15, 3363–3383.
• I. Góral, T. Wichur, E. Sługocka, P. Grygier, M. Głuch-Lutwin, B. Mordyl, E. Honkisz-Orzechowska, N. Szałaj, J. Godyń, D. Panek, P. Zaręba, A. Sarka, P. Żmudzki, G. Latacz, K. Pustelny, A. Bucki, A. Czarna, F. Menezes, A. Więckowska, “Exploring Novel GSK-3β Inhibitors for Anti-Neuroinflammatory and Neuroprotective Effects: Synthesis, Crystallography, Computational Analysis, and Biological Evaluation” ACS Chem. Neurosci. 2024, 15, 3181–3201.
• M. Stefaniak-Napieralska, K. Walczynski, M. Iwan, A. Korga-Plewko, N. Szalaj, A. Wieckowska, M. Staszewski, “Preliminary studies of 1,5-benzoxazepine derivatives as potential histamine H3 receptor antagonists” Future Med. Chem. 2024, 16, 197–204.
• B. Michalska, M. Dzięgielewski, J. Godyń, T. Werner, M. Bajda, T. Karcz, K. Szczepańska, H. Stark, A. Więckowska, K. Walczyński, M. Staszewski, “4-Oxypiperidine Ethers as Multiple Targeting Ligands at Histamine H3 Receptors and Cholinesterases” ACS Chem. Neurosci. 2024, 15, 1206–1218.

2023

• K. Sałat, P. Zaręba, M. Awtoniuk, R. Sałat, “Naturally Inspired Molecules for Neuropathic Pain Inhibition-Effect of Mirogabalin and Cebranopadol on Mechanical and Thermal Nociceptive Threshold in Mice” Molecules 2023, 28
• D. Stary, E. Nepovimova, K. Kuca, M. Bajda, “Searching for new mTOR kinase inhibitors: Analysis of binding sites and validation of docking protocols” Chem. Biol. Drug Des. 2023, 101, 103–119
• J. Kukułowicz, K. Pietrzak-Lichwa, K. Klimonczyk, N. Idlin, M. Bajda, “The SLC6A15–SLC6A20 Neutral Amino Acid Transporter Subfamily: Functions, Diseases, and Their Therapeutic Relevance” Pharmacol. Rev. 2024, 76
• D. Stary, M. Bajda, “Taurine and Creatine Transporters as Potential Drug Targets in Cancer Therapy” Int. J. Mol. Sci. 2023, 24
• P. Zaręba, K. Łątka, G. Mazur, B. Gryzło, A. Pasieka, J. Godyń, D. Panek, A. Skrzypczak-Wiercioch, G. C. Höfner, G. Latacz, M. Maj, A. Espargaró, R. Sabaté, K. Jóźwiak, K. T. Wanner, K. Sałat, B. Malawska, K. Kulig, M. Bajda, “Discovery of novel multifunctional ligands targeting GABA transporters, butyrylcholinesterase, β-secretase, and amyloid β aggregation as potential treatment of Alzheimer’s disease” Eur. J. Med. Chem. 2023, 261
• D. Panek, A. Pasieka, G. Latacz, P. Zaręba, M. Szczęch, J. Godyń, F. Chantegreil, F. Nachon, X. Brazzolotto, A. Skrzypczak-Wiercioch, M. Walczak, M. Smolik, K. Sałat, G. Höfner, K. Wanner, A. Więckowska, B. Malawska, “Discovery of new, highly potent and selective inhibitors of BuChE – design, synthesis, in vitro and in vivo evaluation and crystallography studies” Eur. J. Med. Chem. 2023, 249
• W. Wei, L. Jing, Y. Tian, A. Więckowska, D. Kang, B. Meng, D. Panek, J. Godyń, I. Góral, Y. Song, X. Liu, P. Zhan, “Multifunctional agents against Alzheimer’s disease based on oxidative stress: Polysubstituted pyrazine derivatives synthesized by multicomponent reactions” Bioorg. Med. Chem. 2023, 96
• M. Staszewski, M. Iwan, T. Werner, M. Bajda, J. Godyń, G. Latacz, A. Korga-Plewko, J. Kubik, N. Szałaj, H. Stark, B. Malawska, A. Więckowska, K. Walczyński, “Guanidines: Synthesis of Novel Histamine H3R Antagonists with Additional Breast Anticancer Activity and Cholinesterases Inhibitory Effect” Pharmaceuticals (Basel) 2023, 16
• A. Pasieka, D. Panek, P. Zaręba, E. Sługocka, N. Gucwa, A. Espargaró, G. Latacz, N. Khan, A. Bucki, R. Sabaté, A. Więckowska, B. Malawska, “Novel drug-like fluorenyl derivatives as selective butyrylcholinesterase and β-amyloid inhibitors for the treatment of Alzheimer’s disease” Bioorg. Med. Chem. 2023, 88–89
• D. Łażewska, M. Kaleta, P. Zaręba, J. Godyń, M. Dubiel, E. Honkisz-Orzechowska, A. Doroz-Płonka, A. Więckowska, H. Stark, K. Kieć-Kononowicz, “Multitargeting Histamine H3 Receptor Ligands among Acetyl- and Propionyl-Phenoxyalkyl Derivatives” Molecules

2022

• Stary, D.; Kukułowicz, J.; Góral, I.; Baltrukevich, H.; Barbasevich, M.; Godyń, J.; Bajda, M.; Multilevel virtual screening approach for discovery of thymidine phosphorylase inhibitors as potential anticancer agents, Mol. Struct. 2022, 1249: 131648
• Łątka, K.; Bajda, M.; Analysis of binding determinants for different classes of competitive and noncompetitive inhibitors of glycine transporters, J. Mol. Sci. 2022, 23: 8050
• Chałupnik, P.; Vialko, A.; Pickering, D.S.; Hinkkanen, M.; Donbosco, S.; Moller, T.C.; Jensen, A.A.; Nielsen, B.; Bay, Y.; Kristensen, A.S.; Johansen, T.N.; Łątka, K.; Bajda, M.; Szymańska, E.; Discovery of the first highly selective antagonist of the GluK3 kainate receptor subtype, J. Mol. Sci. 2022, 23: 8050
• Łątka, K.; Bajda, M.; Analysis of different binding modes for tiagabine within the GAT-1 transporter, Biomolecules 2022, 12(11), 1663
• Więckowski, K.; Szałaj, N.; Gryzło, B.; Wichur, T.; Góral, I.; Sługocka, E.; Sniecikowska, J.; Latacz, G.; Siwek, A.; Godyń, J.; et al. Serotonin 5-HT6 Receptor Ligands and Butyrylcholinesterase Inhibitors Displaying Antioxidant Activity—Design, Synthesis and Biological Evaluation of Multifunctional Agents against Alzheimer’s Disease.  J. Mol. Sci.2022, 23, 9443.
• Chrienova, Z.; Rysanek, D.; Oleksak, P.; Stary, D.; Bajda, M.; Reinis, M.; Mikyskova, R.; Novotny, O.; Andrys, R.; Skarka, A.; Vasicova, P.; Novak, J.; Valis, M.; Kuca, K.; Hodny, Z.; Nepovimova, E.; Discovery of small molecule mTOR inhibitors as anti-aging and anti-cancer therapeutics, Aging Neurosci. 2022, 14: 1048260
• Szałaj, N.; Benediktsdottir, A.; Rusin, D.; Karlén, A.; Mowbray, S. M; Więckowska, A. Bacterial type I signal peptidase inhibitors – Optimized hits from nature.  J. Med. Chem.2022, 238, 11449

2021

• Godyń, J.; Zaręba, P.; Łażewska, D.; Stary, D.; Reiner-Link, D.; Frank, A.; Latacz, G.; Mogilski, S.; Kaleta, M.; Doroz-Płonka, A.; Lubelska, A.; Honkisz-Orzechowska, E.; Olejarz-Maciej, A.; Handzlik, J.; Stark, H.; Kieć-Kononowicz, K.; Malawska, B.; Bajda, M. Cyanobiphenyls: Novel H3receptor ligands with cholinesterase and MAO B inhibitory activity as multitarget compounds for potential treatment of Alzheimer’s disease. Bioorganic Chemistry, 2021, 114, 105129
• Gryzło, G.; Zaręba, P.; Malawska, K.; Mazur, G.; Rapacz, A.; Ła̧tka, K.; Höfner, G.C.; Latacz, G.; Bajda, M.; Sałat, K.; Wanner, K.T.; Malawska, B.; Kulig, K. Novel Functionalized Amino Acids as Inhibitors of GABA Transporters with Analgesic Activity, ACS Chem. Neurosci., 2021, 12, 16, 3073–3100
• Jończyk, J.; Kukułowicz, J.; Łątka, K.; Malawska, B.; Jung, YS.; Musilek, K.; Bajda, M. Molecular Modeling Studies on the Multistep Reactivation Process of Organophosphate-Inhibited Acetylcholinesterase and Butyrylcholinesterase., Biomolecules, 2021, 11(2), 169
• Lee, HM.; Andrys, R.; Jonczyk, J.; Kim, K.; Vishakantegowda, A.G.; Malinak, D.; Skarka, A.; Schmidt, M.; Vaskova, M.; Latka, K.; Bajda, M.; Jung, Y.S.; Malawska, B.; Musilek, K. Pyridinium-2-carbaldoximes with quinolinium carboxamide moiety are simultaneous reactivators of acetylcholinesterase and butyrylcholinesterase inhibited by nerve agent surrogates. J Enzyme Inhib Med Chem, 2021, 36(1) 437-449
• Łażewska, D.; Zaręba, P.; Godyń, J.; Doroz-Płonka, A.; Frank, A.; Reiner-Link, D.; Bajda, M.; Stary, D.; Mogilski, S.; Olejarz-Maciej, A.; Kaleta, M.; Stark, H.; Malawska, B.; Kieć-Kononowicz, K. Biphenylalkoxyamine Derivatives-Histamine H3Receptor Ligands with Butyrylcholinesterase Inhibitory Activity. Molecules. 2021, 26(12), 3580
• Rabarijoely, S.; Lech, M.; Bajda, M. Determination of Relative Density and Degree of Saturation in Mineral Soils Based on In Situ Tests. Materials (Basel). 2021, 14(22),
• Skrzypek, A.; Matysiak, J.; Karpińska, M.; Czarnecka, K.; Kręcisz, P.; Stary, D.; Kukułowicz, J.; Paw, B.; Bajda, M.; Szymański, P.; Niewiadomy, A. Bioorg Chem. 2021, 107, 104617
• Stary, D.; Kukułowicz, J.; Góral, I.; Baltrukevich, H.; Barbasevich, M.; Godyń, J.; Bajda, M. Multilevel Virtual Screening Approach for Discovery of Thymidine Phosphorylase Inhibitors as Potential Anticancer Agents.  Mol. Struct.2021, 1249, 131648
• Staszewski, M.; Nelic, D.; Jończyk, J.; Dubiel, M.; Frank, A.; Stark, H.; Bajda, M.; Jakubik, J.; Walczyński, K. Guanidine Derivatives: How Simple Structural Modification of Histamine H3R Antagonists Has Led to the Discovery of Potent Muscarinic M2R/M4R Antagonists. ACS Chem Neurosci, 2021, 12(13), 2503-2519
• Wichur, T.; Pasieka, A.; Godyń, J.; Panek, D.; Góral, I.; Latacz, G.; Honkisz-Orzechowska, E.; Bucki, A.; Siwek, A.; Głuch-Lutwin, M.; Knez, D.; Brazzolotto, X.; Gobec, S.; Kołaczkowski, M.; Sabate, R.; Malawska, B.; Więckowska, A. Discovery of 1-(phenylsulfonyl)-1H-indole-based multifunctional ligands targeting cholinesterases and 5-HT6 receptor with anti-aggregation properties against amyloid-beta and tau. Eur J Med Chem., 2021,225, 113783
• Wichur, T.; Godyń, J.; Góral, I.; Latacz, G.; Bucki, A.; Siwek, A.; Głuch-Lutwin, M.; Mordyl, B.; Śniecikowska, J.; Walczak, M.; Knez, D.; Jukič, M.; Sałat, K.; Gobec, S.; Kołaczkowski, M.; Malawska, B.; Brazzolotto, X.; Więckowska, A.; Development and crystallography-aided SAR studies of multifunctional BuChE inhibitors and 5-HT6R antagonists with β-amyloid anti-aggregation properties. Eur J Med Chem., 2021, 225, 113792
• Zagórska, A.; Czopek, A.; Jaromin, A.; Mielczarek-Puta, M.; Struga, M.; Stary, D.; Bajda, M. Design, Synthesis, and In Vitro Antiproliferative Activity of Hydantoin and Purine Derivatives with the 4-Acetylphenylpiperazinylalkyl Moiety. Materials (Basel)., 2021, 14(15), 4156
• Zaręba, P.; Sałat, K.; Höfner, GC.; Łątka, K.; Bajda, M.; Latacz, G.; Kotniewicz, K.; Rapacz, A.; Podkowa, A.; Maj, M.; Jóźwiak, K.; Filipek, B.; Wanner, KT.; Malawska, B.; Kulig, K. Development of tricyclic N-benzyl-4-hydroxybutanamide derivatives as inhibitors of GABA transporters mGAT1-4 with anticonvulsant, antinociceptive, and antidepressant activity. Eur J Med Chem. 2021, 221, 113512