Research Topics

Application of mathematical modelling and computational intelligence tools in pharmaceutical sciences

Methodology

PBPK models, QSAR, systematic reviews and meta-analyses

Research Equipment

A cluster of over a dozen servers with an automated computation distribution system

Selected Publications

Krumpholz, L., Polak, S., Wiśniowska, B. Use of PBPK modelling to extrapolate in vitro porcine ear skin permeability to in vivo human dermal absorption. IJP 684, 126168, 2025. https://doi.org/10.1016/j.ijpharm.2025.126168

Krumpholz, L., Polak, S., Wiśniowska, B. “IVPT Data Heterogeneity – How to Make Sense of It Using the PBPK Model.” Acta Poloniae Pharmaceutica – Drug Research, Vol. 81, No. 6, 2024, pp. 959–971. https://doi.org/10.32383/appdr/200889

Ongoing Projects

VITAL – VIrtual Twins as tools for personalised clinicAL care (Horizon programme, 2023–2028)

PRELUDIUM22 – Modeling of the excipients effect on drug skin permeability