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Defended Doctorates and Master’s Theses

The main criterion for admission in master’s theses is the grade obtained in the Biology in Pharmaceutical Sciences (Biochemistry) course and participation in the Scientific Student Society.

Master’s theses topics in Pharmacy:

  • Comparison of microbial biotransformation pathways of selected drugs used to treat CNS disorders (2024);
  • Assessment of selected cytoprotective properties purine-2,6-dione derivatives in a rat model cardiomyoblast (2024);
  • Biotransformation of selected non-steroidal anti-inflammatory drugs using the fungus Trametes versicolor (2024);
  • Evaluation of the cardioprotective mechanism of PDE inhibitors in anthracyclines-induced toxicity in human cardiomyocytes (2024);
  •  Cardioprotective mechanisms evaluation of selected compounds in anthracycline induced toxicity in cardiomyocyte model (2023);
  • Biodegradation of gemfibrozil using filamentous fungi of the genus Cunninghamella (2023);
  • Microbial biotransformation of selected non-steroidal anti-inflammatory drugs – identification of metabolites and assessment of their toxicity (2023);
  • The in silico study on the safety of metabolites of selected drugs used in the treatment of civilization diseases (2022);
  • Study on the cell death mechanism induced by cinnamic acid derivatives in combination with doxorubicin (2022);
  • The study of the influence of a new hydrazide purine-2,6-dione derivative on the epithelial-mesenchymal transition of human lung cancer cells (2021);
  • Study of the effect of cinnamic acid derivatives on antioxidant status and inflammatory processes in a cell model of cardiomyocytes and macrophages (2021);
  • Evaluation of the chemosensitizing activity of selected cinnamic acid derivatives in a non-small cell lung cancer cellular model (2020);

Master’s thesis topics in Cosmetology

  • Phototoxicity studies of selected arylidene derivatives of xanthone with photoprotective effects (2024);
  • Cytotoxicity and photocytotoxicity study of selected arene derivatives in the context of application in photodynamic therapy of melanoma (2024);
  • Studies on the photostability of selected arene derivatives with potential application in photodynamic therapy (2024);
  • Hyaluronic acid as a rejuvenating substance used in aesthetic medicine and cosmetology (2023);
  • Phototoxicity study of new melanogenesis inhibitors using Balb/c 3T3 mouse fibroblast cell line (2023);
  • Evaluation of the chemopreventive effect of centella asiatica extracts in a model of melanoma cells (2023);
  • In silico safety assessment of the potential metabolites of selected photoprotective substances (2022);
  • The cosmetological significance of proteins and peptides (2021);
  • Investigation of the antioxidant properties of potential UV filters from the group of xanthon thiol derivatives (2021);
  • Usage of micronucleus test in genotoxicity studies of new compounds with potential photoprotective activity (2021);
  • Safety assessment of new potential UV filters from xanthone-derivatives on in vitro cell models (2020);
  • Assessment of the effect of trans-cinnamaldehyde on human skin cells (2020);
  • Evaluation of metabolic stability of new UV filters in the group of arylidenehydantoin derivatives (2020);
  • Collagen applications in cosmetology (2020);

 

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