The Department of Pharmaceutical Microbiology conducts interdisciplinary research combining microbiological diagnostics and pharmaceutical microbiology.

The ongoing scientific projects include:

Research on New Antibacterial Substances

The department conducts  research on new compounds with antibacterial and antibiofilm activity, targeting bacteria that pose significant therapeutic challenges, including Enterococcus spp., Staphylococcus aureus, Staphylococcus epidermidis, Acinetobacter baumannii, and Helicobacter pylori.

Research on Adjuvants Enhancing Antibiotic Activity

The department investigates new strategies to support antibacterial therapy, including compounds with antibiotic adjuvant activity. The aim of this research is to identify substances that can enhance the effectiveness of antibacterial drugs by inhibiting bacterial resistance mechanisms, including blocking efflux pumps and modulating antibiotic target sites. These studies focus on bacteria such as Enterococcus spp., Staphylococcus aureus, Staphylococcus epidermidis, Escherichia coli, and Klebsiella aerogenes. The antibiotic adjuvants identified so far include derivatives of hydantoin and imidazolone.

Analysis of Antibiotic Resistance Mechanisms and Virulence Factors of Clinical Pathogens

The research involves analyzing genetic determinants of resistance and virulence factors of various pathogens, such as Helicobacter pylori, Enterococcus spp., and Mycobacterium spp. The applied methods include molecular techniques (PCR, RT-PCR, sequencing) and phenotypic analyses.

Epidemiology of Infections and Clinical Data Analysis

The department conducts studies on the occurrence and spread of pathogens in both hospital and community settings. Examples include the epidemiological analysis of Klebsiella pneumoniae and Escherichia coli infections in hospital environments, as well as the epidemiology of HIV infection in Poland.

Analysis of Antibacterial Properties of Biomaterials and Nanoparticles

The research includes the evaluation of antimicrobial biomaterials used in regenerative medicine, implantology, and infection treatment. The studies focus on biomaterials that limit bacterial biofilm formation and on analyzing the synergistic effects of silver nanoparticles with antibiotics.