Defended Doctorates and Master’s Theses

Master’s theses topics in Pharmacy:

  • Comparison of microbial biotransformation pathways of selected drugs used to treat CNS disorders (2024);
  • Assessment of selected cytoprotective properties purine-2,6-dione derivatives in a rat model cardiomyoblast (2024);
  • Biotransformation of selected non-steroidal anti-inflammatory drugs using the fungus Trametes versicolor (2024);
  • Evaluation of the cardioprotective mechanism of PDE inhibitors in anthracyclines-induced toxicity in human cardiomyocytes (2024);
  •  Cardioprotective mechanisms evaluation of selected compounds in anthracycline induced toxicity in cardiomyocyte model (2023);
  • Biodegradation of gemfibrozil using filamentous fungi of the genus Cunninghamella (2023);
  • Microbial biotransformation of selected non-steroidal anti-inflammatory drugs – identification of metabolites and assessment of their toxicity (2023);
  • The in silico study on the safety of metabolites of selected drugs used in the treatment of civilization diseases (2022);
  • Study on the cell death mechanism induced by cinnamic acid derivatives in combination with doxorubicin (2022);
  • The study of the influence of a new hydrazide purine-2,6-dione derivative on the epithelial-mesenchymal transition of human lung cancer cells (2021);
  • Study of the effect of cinnamic acid derivatives on antioxidant status and inflammatory processes in a cell model of cardiomyocytes and macrophages (2021);
  • Evaluation of the chemosensitizing activity of selected cinnamic acid derivatives in a non-small cell lung cancer cellular model (2020);

Master’s thesis topics in Cosmetology

  • Phototoxicity studies of selected arylidene derivatives of xanthone with photoprotective effects (2024);
  • Cytotoxicity and photocytotoxicity study of selected arene derivatives in the context of application in photodynamic therapy of melanoma (2024);
  • Studies on the photostability of selected arene derivatives with potential application in photodynamic therapy (2024);
  • Hyaluronic acid as a rejuvenating substance used in aesthetic medicine and cosmetology (2023);
  • Phototoxicity study of new melanogenesis inhibitors using Balb/c 3T3 mouse fibroblast cell line (2023);
  • Evaluation of the chemopreventive effect of centella asiatica extracts in a model of melanoma cells (2023);
  • In silico safety assessment of the potential metabolites of selected photoprotective substances (2022);
  • The cosmetological significance of proteins and peptides (2021);
  • Investigation of the antioxidant properties of potential UV filters from the group of xanthon thiol derivatives (2021);
  • Usage of micronucleus test in genotoxicity studies of new compounds with potential photoprotective activity (2021);
  • Safety assessment of new potential UV filters from xanthone-derivatives on in vitro cell models (2020);
  • Assessment of the effect of trans-cinnamaldehyde on human skin cells (2020);
  • Evaluation of metabolic stability of new UV filters in the group of arylidenehydantoin derivatives (2020);
  • Collagen applications in cosmetology (2020);